A new clinical guideline from the American Gastroenterological Association (AGA), published February 9, 2018 in Gastroenterology focuses on the critical decisions made during initial management of acute pancreatitis. Key recommendations include goal-directed therapy for fluid management, early (within 24 hours) oral feeding as tolerated rather than keeping the patient nil by mouth and enteral rather than parenteral nutrition in patients who are unable to take orally.